SLC7A8 antibody [4H10]

Cannot supply to this region.

SKU:: GTX83621
Additional Names:: solute carrier family 7 member 8 , LAT2 , LPI-PC1
Application:: Flow Cytometry, IF, ICC, IP
Concentration:: 0.65 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human SLC7A8 (NP_036376) produced in HEK293T cell.
Clone:: 4H10
Uniprot:: Q9UHI5
Synonyms:: integral membrane protein E16H;L-type amino acid transporter 2;large neutral amino acids transporter small subunit 2;LAT2;LPI-PC1;solute carrier family 7 (amino acid transporter light chain, L system), member 8;solute carrier family 7 (amino acid transporter, L-type), member 8;solute carrier family 7 (cationic amino acid transporter, y+ system), member 8;Solute carrier family 7 member 8
Extra Details:: Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

Shipping Conditions:: Blue Ice