RTN3 antibody [1E11]

Cannot supply to this region.

SKU:: GTX83351
Additional Names:: reticulon 3 , ASYIP , HAP , NSPL2 , NSPLII , RTN3-A1
Application:: ELISA, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of RTN3 expressed in E. Coli.
Clone:: 1E11
Uniprot:: O95197
Synonyms:: ASY interacting protein;ASYIP;HAP;homolog of ASY protein;neuroendocrine-specific protein-like 2;neuroendocrine-specific protein-like II;NSP-like protein 2;NSP-like protein II;NSPL2;NSPLII;reticulon-3;RTN3-A1
Extra Details:: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]

Shipping Conditions:: Blue Ice