Estrogen Receptor alpha antibody [2B7]

Cannot supply to this region.

SKU:: GTX83349
Additional Names:: estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
Application:: ELISA, WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
Clone:: 2B7
Uniprot:: P03372
Synonyms:: E2 receptor alpha;ER;ER-alpha;Era;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha
Extra Details:: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Shipping Conditions:: Blue Ice