MLH1 antibody [4C9C7]

Cannot supply to this region.

SKU:: GTX83336
Additional Names:: mutL homolog 1 , COCA2 , FCC2 , HNPCC , HNPCC2 , hMLH1
Application:: ELISA, WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli.
Clone:: 4C9C7
Uniprot:: P40692
Synonyms:: COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2;MutL protein homolog 1
Extra Details:: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]