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  2. Monoclonal

GTX83321

TrkC antibody [7H6]

Cannot supply to this region.

SKU:
GTX83321
Additional Names:
neurotrophic receptor tyrosine kinase 3 , GP145-TrkC , TRKC , gp145(trkC)
Application:
ELISA, WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
Ascites, 0.03% Sodium azide.
Immunogen:
Purified recombinant extracellular fragment of human TrkC (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
Clone:
7H6
Uniprot:
Q16288
Synonyms:
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein;ETV6-NTRK3 fusion;GP145-TrkC;gp145(trkC);Neurotrophic tyrosine kinase receptor type 3;neurotrophic tyrosine kinase, receptor, type 3;NT-3 growth factor receptor;TRKC;TrkC tyrosine kinase;tyrosine kinase receptor C
Extra Details:
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Shipping Conditions:
Blue Ice