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![PRAK antibody [7H10B4]](https://www.genetex.com/upload/website/prouct_img/normal/GTX83275/GTX83275_20170912_WB_w_23061322_966.webp)
GTX83275
PRAK antibody [7H10B4]
Cannot supply to this region.
- SKU:
- GTX83275
- Additional Names:
- mitogen-activated protein kinase-activated protein kinase 5 , MAPKAP-K5 , MK-5 , MK5 , PRAK
- Application:
- ELISA, WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Unpurified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Ascites, 0.03% Sodium azide.
- Immunogen:
- Purified recombinant fragment of PRAK expressed in E. Coli.
- Clone:
- 7H10B4
- Uniprot:
- Q8IW41
- Synonyms:
- MAP kinase-activated protein kinase 5;MAPKAP kinase 5;MAPKAP-K5;MAPKAPK-5;mitogen-activated protein kinase-activated protein kinase 5;MK-5;MK5;p38-regulated/activated protein kinase;PRAK
- Extra Details:
- The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
- Shipping Conditions:
- Blue Ice