MAP4K4 antibody [4H9E7]

Cannot supply to this region.

SKU:: GTX83190
Additional Names:: mitogen-activated protein kinase kinase kinase kinase 4 , FLH21957 , HEL-S-31 , HGK , MEKKK4 , NIK
Application:: ELISA, WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
Clone:: 4H9E7
Uniprot:: O95819
Synonyms:: epididymis secretory protein Li 31;FLH21957;HEL-S-31;hepatocyte progenitor kinase-like/germinal center kinase-like kinase;HGK;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK4;mitogen-activated protein kinase kinase kinase kinase 4;nck-interacting kinase;NIK;Ste20 group protein kinase HGK
Extra Details:: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice