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  2. Monoclonal

GTX83168

NCOR1 antibody [7A7A9]

Cannot supply to this region.

SKU:
GTX83168
Additional Names:
nuclear receptor corepressor 1 , N-CoR , N-CoR1 , PPP1R109 , TRAC1 , hN-CoR
Application:
ELISA, WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
Ascites, 0.03% Sodium azide.
Immunogen:
Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.
Clone:
7A7A9
Uniprot:
O75376
Synonyms:
hN-CoR;N-CoR;N-CoR1;nuclear receptor corepressor 1;PPP1R109;protein phosphatase 1, regulatory subunit 109;thyroid hormone- and retinoic acid receptor-associated corepressor 1;TRAC1
Extra Details:
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
Shipping Conditions:
Blue Ice