Factor VIII antibody [5E9B2]

Cannot supply to this region.

SKU:: GTX83141
Additional Names:: coagulation factor VIII , AHF , DXS1253E , F8B , F8C , FVIII , HEMA
Application:: ELISA, WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of F8 expressed in E. Coli.
Clone:: 5E9B2
Uniprot:: P00451
Synonyms:: AHF;antihemophilic factor;coagulation factor VIII;coagulation factor VIII A1 domain;coagulation factor VIII C2 domain;coagulation factor VIII, procoagulant component;coagulation factor VIIIc;DXS1253E;F8B;F8C;factor VIII F8B;FVIII;HEMA;Procoagulant component
Extra Details:: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice