FMRP antibody [4G9]

Cannot supply to this region.

SKU:: GTX83130
Additional Names:: fragile X mental retardation 1 , FMRP , FRAXA , POF , POF1
Application:: ELISA, WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human FMRP expressed in E. Coli.
Clone:: 4G9
Uniprot:: Q06787
Synonyms:: FMRP;fragile X mental retardation 1;fragile X mental retardation protein 1;FRAXA;POF;POF1;synaptic functional regulator FMR1;truncated FMRP
Extra Details:: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]