SMC1 antibody [5B6]

Cannot supply to this region.

SKU:: GTX82813
Additional Names:: structural maintenance of chromosomes 1A , CDLS2 , DXS423E , SB1.8 , SMC1 , SMC1L1 , SMC1alpha , SMCB
Application:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human SMC1 expressed in E. Coli.
Clone:: 5B6
Uniprot:: Q14683
Synonyms:: CDLS2;DEE85;DXS423E;EIEE85;epididymis secretory sperm binding protein;SB1.8;segregation of mitotic chromosomes 1;SMC protein 1A;SMC-1-alpha;SMC1;SMC1 (structural maintenance of chromosomes 1, yeast)-like 1;SMC1alpha;SMC1L1;SMCB;structural maintenance of chromosomes protein 1A
Extra Details:: Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice