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  2. Monoclonal

GTX82806

PRMT6 antibody [4G2]

Cannot supply to this region.

SKU:
GTX82806
Additional Names:
protein arginine methyltransferase 6 , HRMT1L6
Application:
ELISA, WB
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
Ascites, 0.03% Sodium azide.
Immunogen:
Purified recombinant fragment of human PRMT6 expressed in E. Coli.
Clone:
4G2
Uniprot:
Q96LA8
Synonyms:
heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;histone-arginine N-methyltransferase PRMT6;HMT1 hnRNP methyltransferase-like 6;HRMT1L6;protein arginine N-methyltransferase 6
Extra Details:
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Shipping Conditions:
Blue Ice