SMAD4 antibody [4G1C6]

Cannot supply to this region.

SKU:: GTX82787
Additional Names:: SMAD family member 4 , DPC4 , JIP , MADH4 , MYHRS
Application:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human SMAD4 expressed in E. Coli.
Clone:: 4G1C6
Uniprot:: Q13485
Synonyms:: deleted in pancreatic carcinoma locus 4;deletion target in pancreatic carcinoma 4;DPC4;JIP;MAD homolog 4;MADH4;mothers against decapentaplegic homolog 4;mothers against decapentaplegic, Drosophila, homolog of, 4;MYHRS;SMAD family member 4;SMAD, mothers against DPP homolog 4
Extra Details:: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]

Shipping Conditions:: Blue Ice