GTX82708
Dopamine beta Hydroxylase antibody, C-Term
Cannot supply to this region.
- SKU:
- GTX82708
- Additional Names:
- dopamine beta-hydroxylase , DBM , ORTHYP1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Sheep
- Reactivities:
- Human, Mouse
- Buffer:
- 10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol, no preservatives.
- Immunogen:
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
- Uniprot:
- P09172
- Synonyms:
- DBM;dopamine beta-hydroxylase;dopamine beta-hydroxylase (dopamine beta-monooxygenase);Dopamine beta-monooxygenase;ORTHYP1
- Extra Details:
- The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]
- Shipping Conditions:
- Blue Ice