Thyroid Hormone Receptor beta antibody [2386]

Cannot supply to this region.

SKU:: GTX82578
Additional Names:: thyroid hormone receptor beta , C-ERBA-2 , C-ERBA-BETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB1 , THRB2
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: 10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol, no preservatives.
Immunogen:: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Clone:: 2386
Uniprot:: P10828
Synonyms:: C-ERBA-2;C-ERBA-BETA;ERBA2;GRTH;NR1A2;nuclear receptor subfamily 1 group A member 2;oncogene ERBA2;PRTH;THR1;THRB1;THRB2;thyroid hormone nuclear receptor beta variant 1;thyroid hormone receptor beta;thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian);TRbeta
Extra Details:: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice