Actin antibody [BA3R]

Cannot supply to this region.

SKU:: GTX82559
Additional Names:: PS1TP5BP1 , beta cytoskeletal actin , Beta-actin , Betaactin , actin , beta , PS1TP5-binding protein 1 , actin , cytoplasmic1 , actin , cytoplasmic 1 , PS1TP5binding protein1 , PS1TP5binding protein 1 , Beta actin , PS1TP5 binding protein 1
Application:: ELISA, IHC, WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Rabbit, Rat
Buffer:: PBS, no preservatives.
Immunogen:: B Beta-Actin N-terminal peptide-KLH conjugates
Clone:: BA3R
Synonyms:: actin, cytoplasmic 1;beta cytoskeletal actin;BRWS1;I(2)-actin;PS1TP5-binding protein 1;PS1TP5BP1
Extra Details:: Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is foundin two main states; G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G-and F-actin are intrinsically flexible structures - a feature vital in actin's role as a dynamic filamentnetwork. Actin has four major functions. Firstly, F-actin polymers form microfilaments - polar intracellular'tracks' for kinesin motor proteins, allowing the transport of vesicles, organelles and other cargo. Actinis a component of the cytoskeleton and links to alpha-actinin, E-cadherin and beta-catenin at adherensjunctions. This gives mechanical support to cells and attaches them to each other and the extracellularmatrix. In muscle cells, actin-rich thin filaments associate with myosin-rich thick filaments to formactomyosin myofibrils. Using energy from the hydrolysis of ATP, myofibrils undergo cyclic shortening throughactin-myosin head interactions, which represents the mechanics of muscle contraction. Finally, actin has arole in cell motility through polymerization and depolymerization of fibrils.

Shipping Conditions:: Blue Ice