PRX III antibody

Cannot supply to this region.

SKU:: GTX82299
Additional Names:: peroxiredoxin 3 , AOP-1 , AOP1 , HBC189 , MER5 , PRO1748 , SP-22 , prx-III
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Chicken/Avian
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Immunogen Sequence: GI # 5802974, sequence 1-256 Recombinant peroxiredoxin 3 isoform a
Uniprot:: P30048
Synonyms:: antioxidant protein 1;AOP-1;AOP1;epididymis secretory sperm binding protein;HBC189;MER5;peroxiredoxin III;Peroxiredoxin-3;PRO1748;protein MER5 homolog;prx-III;SP-22;thioredoxin-dependent peroxide reductase, mitochondrial;thioredoxin-dependent peroxiredoxin 3
Extra Details:: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. This protein is a protein with antioxidant function and is localized in the mitochondrion. This protein shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved. and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation. differentiation. and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Shipping Conditions:: Blue Ice