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  2. Polyclonal

GTX81955

MDH1 antibody, C-term

Cannot supply to this region.

SKU:
GTX81955
Additional Names:
malate dehydrogenase 1 , HEL-S-32 , MDH-s , MDHA , MGC:1375 , MOR2
Application:
Flow Cytometry, WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
SAS Precipitated; Dialysis
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 0.09% Sodium azide.
Immunogen:
KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human MDH1.
Uniprot:
P40925
Synonyms:
cytosolic malate dehydrogenase;DEE88;diiodophenylpyruvate reductase;EIEE88;epididymis secretory protein Li 32;HEL-S-32;KAR;malate dehydrogenase 1, NAD (soluble);malate dehydrogenase, cytoplasmic;malate dehydrogenase, peroxisomal;MDH-s;MDHA;MGC:1375;MOR2;soluble malate dehydrogenase
Extra Details:
This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]
Shipping Conditions:
Blue Ice