Caldesmon antibody, Internal

Cannot supply to this region.

SKU:: GTX81812
Additional Names:: caldesmon 1 , CDM , H-CAD , HCAD , L-CAD , LCAD , NAG22
Application:: Flow Cytometry, WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: SAS Precipitated; Dialysis
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.
Uniprot:: Q05682
Synonyms:: caldesmon;CDM;H-CAD;HCAD;L-CAD;LCAD;NAG22;testis secretory sperm-binding protein Li 227n
Extra Details:: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]