GTX81538
Glutaredoxin 2 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX81538
- Additional Names:
- glutaredoxin 2 , CGI-133 , GRX2
- Application:
- Flow Cytometry, WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- SAS Precipitated; Dialysis
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 120-146 amino acids from the C-terminal region of human GLRX2.
- Uniprot:
- Q9NS18
- Synonyms:
- bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2);CGI-133;glutaredoxin (thioltransferase) 2;glutaredoxin 2;GRX2
- Extra Details:
- The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]
- Shipping Conditions:
- Blue Ice