GTX81054
Derlin 1 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX81054
- Additional Names:
- derlin 1 , DER-1 , DER1 , derlin-1
- Application:
- Flow Cytometry, WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified; Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human DERL1.
- Uniprot:
- Q9BUN8
- Synonyms:
- degradation in endoplasmic reticulum protein 1;DER-1;DER1;Der1-like domain family, member 1;Der1-like protein 1;derlin-1;DERtrin-1
- Extra Details:
- The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
- Shipping Conditions:
- Blue Ice