PTPRB antibody [122.2]

Cannot supply to this region.

SKU:: GTX80343
Additional Names:: protein tyrosine phosphatase receptor type B , HPTP-BETA , HPTPB , PTPB , R-PTP-BETA , VEPTP
Application:: WB, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Rat
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Rat
Buffer:: Growth Medium (protein free), concentrated and dialysed against PBS, no preservatives.
Immunogen:: Embryonic rat brain proteoglycans
Clone:: 122.2
Uniprot:: P23467
Synonyms:: HPTP-BETA;HPTPB;protein tyrosine phosphatase, receptor type, beta polypeptide;PTPB;R-PTP-BETA;receptor-type tyrosine-protein phosphatase beta;vascular endothelial protein tyrosine phosphatase;VE-PTP;VEPTP
Extra Details:: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Shipping Conditions:: Blue Ice