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  2. Monoclonal

GTX80217

BRG1 antibody [BRG-01]

Cannot supply to this region.

SKU:
GTX80217
Additional Names:
BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SMARCA4 , SNF2 , SNF2L4 , SNF2LB , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , SWI2 , hSNF2b
Application:
WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1.
Clone:
BRG-01
Uniprot:
P51532
Synonyms:
ATP-dependent helicase SMARCA4;BAF190;BAF190A;brahma protein-like 1;BRG1;BRG1-associated factor 190A;BRM/SWI2-related gene 1;CSS4;global transcription activator homologous sequence;homeotic gene regulator;hSNF2b;mitotic growth and transcription activator;MRD16;nuclear protein GRB1;protein brahma homolog 1;protein BRG-1;RTPS2;SNF2;SNF2-beta;SNF2-like 4;SNF2L4;SNF2LB;sucrose nonfermenting-like 4;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;SWI2;transcription activator BRG1
Extra Details:
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Shipping Conditions:
Blue Ice