beta Catenin antibody [EM-22]

Cannot supply to this region.

SKU:: GTX80159
Additional Names:: CTNNB , CTNNB1 , MRD19 , armadillo , catenin beta 1 , beta Catenin , Catenin-B Beta , B Beta Catenin
Application:: Flow Cytometry, WB, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Hamster, Human, Mouse
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Recombinant human beta-catenin
Clone:: EM-22
Uniprot:: P35222
Synonyms:: armadillo;Beta-catenin;catenin (cadherin-associated protein), beta 1, 88kDa;catenin beta-1;CTNNB;EVR7;MRD19;NEDSDV
Extra Details:: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]