CD177 antibody [MEM-166] (APC)

Cannot supply to this region.

SKU:: GTX79995
Additional Names:: CD177 , CD177 molecule , HNA2A , HNA2a , NB1 , NB1 GP , PRV1
Application:: Flow Cytometry
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Size-exclusion Chromatography
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Human granulocytes
Clone:: MEM-166
Uniprot:: Q8N6Q3
Synonyms:: CD177 antigen;cell surface receptor;HNA-2a;HNA2A;human neutrophil alloantigen 2a;NB1;NB1 glycoprotein;NB1 GP;polycythemia rubra vera protein 1;PRV-1;PRV1
Extra Details:: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]