Renin antibody [7D3-E3]

Cannot supply to this region.

SKU:: GTX79644
Additional Names:: HNFJ2,REN,renin,Renin,Prorenin
Application:: ELISA, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: 50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
Immunogen:: Recombinant full length wild-type human protein (Glycosylated).
Clone:: 7D3-E3
Uniprot:: P00797
Synonyms:: ADTKD4;angiotensin-forming enzyme;angiotensinogenase;HNFJ2;renin;renin precursor, renal;RTD
Extra Details:: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]