GTX79607
tPA antibody (HRP)
Cannot supply to this region.
- SKU:
- GTX79607
- Additional Names:
- PLAT,TPA,plasminogen activator, tissue type,tPA,TPA Tissue Plasminogen Activator
- Application:
- ELISA
- Concentration:
- 2 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Sheep
- Reactivities:
- Human, Porcine
- Buffer:
- PBS, 1% BSA, 0.01% Thimerosal.
- Immunogen:
- Recombinant full length wild-type human protein (Glycosylated).
- Uniprot:
- P00750
- Synonyms:
- alteplase;plasminogen/activator kringle;reteplase;T-PA;t-plasminogen activator;tissue-type plasminogen activator;TPA
- Extra Details:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
- Shipping Conditions:
- Blue Ice