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![Mist1 antibody [6E8/A12/C11P1]](https://www.genetex.com/upload/website/prouct_img/normal/GTX79479/GTX79479_1944_WB_w_23061322_276.webp)
GTX79479
Mist1 antibody [6E8/A12/C11P1]
Cannot supply to this region.
- SKU:
- GTX79479
- Additional Names:
- basic helix-loop-helix family member a15 , BHLHB8 , MIST1
- Application:
- WB, IHC-P, IHC-Fr
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.1% BSA, 0.05% Sodium azide.
- Immunogen:
- Mouse Mist1, C-terminus residues 175-197.
- Clone:
- 6E8/A12/C11P1
- Uniprot:
- Q7RTS1
- Synonyms:
- basic helix-loop-helix domain containing, class B, 8;BHLHB8;class A basic helix-loop-helix protein 15;class B basic helix-loop-helix protein 8;class II bHLH protein MIST1;MIST-1;MIST1;muscle, intestine and stomach expression 1
- Extra Details:
- Mist 1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. This protein also negatively regulates bHLH-mediated transcription through an N-terminal repressor domain, and serves as a key regulator of acinar cell function, stability, and identity. Mist 1 is also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport, and may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.
- Shipping Conditions:
- Blue Ice