GTX79087
EIF4G (phospho Ser1231) antibody
Cannot supply to this region.
- SKU:
- GTX79087
- Additional Names:
- EIF4F,EIF4G,EIF4G1,EIF4GI,P220,PARK18,eukaryotic translation initiation factor 4 gamma 1
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Sequential Chromatography; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized phosphopeptide derived from human eIF4G around the phosphorylation site of serine 1232 (P-V-Sp-P-L).
- Uniprot:
- Q04637
- Synonyms:
- eIF-4-gamma 1;EIF-4G1;EIF4-gamma;EIF4F;EIF4G;EIF4GI;eucaryotic translation initiation factor 4G;eukaryotic translation initiation factor 4 gamma 1;P220;PARK18
- Extra Details:
- The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
- Shipping Conditions:
- Blue Ice