Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Monoclonal

GTX77645

CENPF antibody [7F11.2]

Cannot supply to this region.

SKU:
GTX77645
Additional Names:
centromere protein F , CENF , CILD31 , PRO1779 , STROMS , hcp-1
Application:
IHC, IF, ICC
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein G Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, no preservatives.
Immunogen:
Protein fragment expressed in E. coli corresponding to amino acids 1759-2093.
Clone:
7F11.2
Uniprot:
P49454
Synonyms:
AH antigen;cell-cycle-dependent 350K nuclear protein;CENF;CENP-F kinetochore protein;centromere protein F;centromere protein F, 350/400kDa;CILD31;hcp-1;kinetochore protein CENPF;mitosin;PRO1779;STROMS
Extra Details:
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice