GTX76427
CD59 antibody [YTH53.1] (PE)
Cannot supply to this region.
- SKU:
- GTX76427
- Additional Names:
- CD59 molecule (CD59 blood group) , 16.3A5 , 1F5 , EJ16 , EJ30 , EL32 , G344 , HRF-20 , HRF20 , MAC-IP , MACIF , MEM43 , MIC11 , MIN1 , MIN2 , MIN3 , MIRL , MSK21 , p18-20
- Application:
- Flow Cytometry
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ion Exchange
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Genetex
- Host:
- Rat
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 5% Sucrose, 0.09% Sodium azide.
- Immunogen:
- Human Peripheral Blood T cells.
- Clone:
- YTH53.1
- Uniprot:
- P13987
- Synonyms:
- 16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344);CD59 blood group antigen;CD59 glycoprotein;CD59 molecule, complement regulatory protein;EJ16;EJ30;EL32;G344;HRF-20;HRF20;human leukocyte antigen MIC11;Ly-6-like protein;lymphocytic antigen CD59/MEM43;MAC-inhibitory protein;MAC-IP;MACIF;MEM43;MEM43 antigen;membrane attack complex (MAC) inhibition factor;membrane attack complex inhibition factor;membrane inhibitor of reactive lysis;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18-20;protectin;surface anitgen recognized by monoclonal antibody 16.3A5;T cell-activating protein
- Extra Details:
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice