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  2. Monoclonal

GTX75422

p53 (phospho Ser392) antibody [FP3.2(FPS392)]

Cannot supply to this region.

SKU:
GTX75422
Additional Names:
BCC7 , LFS1 , P53 , TP53 , TRP53 , tumor protein p53 , p53
Application:
WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
KLH-conjugated phosphopeptide RHKKLMFKTEGPDS[P]D, corresponding to amino acids 378-393 of human p53.
Clone:
FP3.2(FPS392)
Uniprot:
P04637
Synonyms:
antigen NY-CO-13;BCC7;BMFS5;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;Tumor suppressor p53;tumor supressor p53
Extra Details:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Shipping Conditions:
Blue Ice