CD105 antibody [SN6] (PE)

Cannot supply to this region.

SKU:: GTX75142
Additional Names:: endoglin , END , HHT1 , ORW1
Application:: Flow Cytometry
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Rabbit, Equine
Buffer:: PBS, 1% BSA, 5% Sucrose, 0.09% Sodium azide.
Immunogen:: Partially purified cell membrane antigens from fresh leukaemia cells.
Clone:: SN6
Uniprot:: P17813
Synonyms:: CD105 antigen;END;endoglin;HHT1;ORW1
Extra Details:: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]