Integrin alpha 6 antibody [450-30A] (PE)

Cannot supply to this region.

SKU:: GTX75047
Additional Names:: integrin subunit alpha 6 , CD49f , ITGA6B , VLA-6
Application:: Flow Cytometry
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 1% BSA, 5% Sucrose, 0.09% Sodium azide.
Immunogen:: integrin a6b4 purified from A431 cells
Clone:: 450-30A
Uniprot:: P23229
Synonyms:: CD49 antigen-like family member F;CD49f;integrin alpha-6;integrin alpha6B;integrin, alpha 6;ITGA6B;VLA-6
Extra Details:: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]