Pancreatic Polypeptide antibody

Cannot supply to this region.

SKU:: GTX73873
Additional Names:: pancreatic polypeptide , PNP , PP
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Synthetic human pancreatic polypeptide conjugated to keyhole limpet hemocyanin.
Uniprot:: P01298
Synonyms:: Pancreatic polypeptide;pancreatic polypeptide Y;pancreatic prohormone;PNP;PP;prepro-PP (prepropancreatic polypeptide)
Extra Details:: This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]