CD68 antibody [PG-M1]

Cannot supply to this region.

SKU:: GTX73723
Additional Names:: CD68 molecule , GP110 , LAMP4 , SCARD1
Application:: IHC, IHC-P, IF, ICC
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: BALB/C mice were immunized with Gaucher's cells.
Clone:: PG-M1
Uniprot:: P34810
Synonyms:: CD68 antigen;gp11;GP110;La;LAMP4;ma;macrophage antigen CD68;macrosialin;Sca;SCARD1;scavenger receptor class D, member 1
Extra Details:: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]