GTX70471
CLACP antibody
Cannot supply to this region.
- SKU:
- GTX70471
- Additional Names:
- collagen type XXV alpha 1 chain , AMY , CFEOM5 , CLAC , CLAC-P , CLACP
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide: NHGFLSADQQLIK, corresponding to amino acids 171-183 of human and mouse CLACP.
- Uniprot:
- Q9BXS0
- Synonyms:
- alzheimer disease amyloid-associated protein;AMY;CFEOM5;CLAC;CLAC-P;CLACP;collagen alpha-1(XXV) chain;collagen-like Alzheimer amyloid plaque component;collagenous Alzheimer amyloid plaque component
- Extra Details:
- This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- Shipping Conditions:
- Blue Ice