CtIP antibody [19E8]

Cannot supply to this region.

SKU:: GTX70264
Additional Names:: RB binding protein 8, endonuclease , COM1 , CTIP , JWDS , RIM , SAE2 , SCKL2
Application:: ChIP, WB, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, 20% Glycerol, no preservatives.
Immunogen:: Human CtIP
Clone:: 19E8
Uniprot:: Q99708
Synonyms:: COM1;CTBP-interacting protein;CTIP;DNA endonuclease RBBP8;JWDS;RBBP-8;retinoblastoma binding protein 8;Retinoblastoma-binding protein 8;Retinoblastoma-interacting protein and myosin-like;RIM;SAE2;SCKL2;sporulation in the absence of SPO11 protein 2 homolog
Extra Details:: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice