TSG101 antibody [4A10]

Cannot supply to this region.

SKU:: GTX70255
Additional Names:: tumor susceptibility 101 , TSG10 , VPS23
Application:: ELISA, Flow Cytometry, IHC, WB, IHC-P, IF, ICC, IP, EM
Concentration:: 1.8 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Fish, Hamster, Human, Mouse, Porcine, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Amino acids 167-374 of TSG101 protein expressed in E. coli.
Clone:: 4A10
Uniprot:: Q99816
Synonyms:: ESCRT-I complex subunit TSG101;TSG10;tumor susceptibility gene 10;tumor susceptibility gene 101;tumor susceptibility gene 101 protein;tumor susceptibility protein;VPS23
Extra Details:: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice