Rad50 antibody [13B3]

Cannot supply to this region.

SKU:: GTX70228
Additional Names:: RAD50 double strand break repair protein , NBSLD , RAD502 , hRad50
Application:: ChIP, IHC, WB, IHC-P, IF, ICC, IP, FuncS
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Amino acids 1-425 of Rad50 expressed in E. coli.
Clone:: 13B3
Uniprot:: Q92878
Synonyms:: DNA repair protein RAD50;hRad50;NBSLD;RAD50 homolog, double strand break repair protein;RAD502
Extra Details:: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]

Shipping Conditions:: Blue Ice