ATR antibody [2B5]

Cannot supply to this region.

SKU:: GTX70109
Additional Names:: ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
Application:: WB, IF, ICC, IP, FuncS
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
Clone:: 2B5
Uniprot:: Q13535
Synonyms:: ataxia telangiectasia and Rad3-related protein;FCTCS;FRAP-related protein 1;FRAP-related protein-1;FRP1;MEC1;MEC1, mitosis entry checkpoint 1, homolog;SCKL;SCKL1;serine/threonine-protein kinase ATR
Extra Details:: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]