Human TIGAR protein, His tag

Cannot supply to this region.

SKU:: GTX68650-PRO
Additional Names:: TP53 induced glycolysis regulatory phosphatase , C12orf5 , FR2BP
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 200mM NaCl, 10% Glycerol, 2mM DTT, no preservatives.
Immunogen:: TP53 induced glycolysis regulatory phosphatase
Species:: Human
Uniprot:: Q9NQ88
Synonyms:: C12orf5;FR2BP;fructose-2,6-bisphosphatase TIGAR;fructose-2,6-bisphosphate 2-phosphatase;probable fructose-2,6-bisphosphatase TIGAR;TP53-induced glycolysis and apoptosis regulator;TP53-induced glycolysis regulatory phosphatase;transactivated by NS3TP2 protein
Extra Details:: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]