GTX68612-PRO
Human TDP1 protein, His tag
Cannot supply to this region.
- SKU:
- GTX68612-PRO
- Additional Names:
- tyrosyl-DNA phosphodiesterase 1
- Concentration:
- 0.25 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- PBS, 10% Glycerol, no preservatives.
- Immunogen:
- tyrosyl-DNA phosphodiesterase 1
- Species:
- Human
- Uniprot:
- Q9NUW8
- Synonyms:
- tyr-DNA phosphodiesterase 1;tyrosyl-DNA phosphodiesterase 1
- Extra Details:
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
- Shipping Conditions:
- Dry Ice