Human RNMTL1 protein, His tag

Cannot supply to this region.

SKU:: GTX68577-PRO
Additional Names:: mitochondrial rRNA methyltransferase 3 , RMTL1 , RNMTL1
Concentration:: 1 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 10% Glycerol, no preservatives.
Immunogen:: mitochondrial rRNA methyltransferase 3
Species:: Human
Uniprot:: Q9HC36
Synonyms:: 16S rRNA (guanosine(1370)-2'-O)-methyltransferase;16S rRNA [Gm1370] 2'-O-methyltransferase;putative RNA methyltransferase;RMTL1;RNA methyltransferase like 1;RNA methyltransferase-like protein 1;RNMTL1;rRNA methyltransferase 3, mitochondrial
Extra Details:: Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]