Human GSKIP protein, His tag

Cannot supply to this region.

SKU:: GTX68514-PRO
Additional Names:: GSK3B interacting protein , C14orf129 , HSPC210
Concentration:: 1 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 50mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
Immunogen:: GSK3B interacting protein
Species:: Human
Uniprot:: Q9P0R6
Synonyms:: C14orf129;GSK3-beta interaction protein;GSK3B-interacting protein;GSK3beta interaction protein;HSPC210
Extra Details:: This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]