Human ASCC1 protein, His tag

Cannot supply to this region.

SKU:: GTX68462-PRO
Additional Names:: activating signal cointegrator 1 complex subunit 1 , ASC1p50 , CGI-18 , SMABF2 , p50
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
Immunogen:: activating signal cointegrator 1 complex subunit 1
Species:: Human
Uniprot:: Q8N9N2
Synonyms:: activating signal cointegrator 1 complex subunit 1;ASC-1 complex subunit P50;ASC1p50;CGI-18;p50;SMABF2;trip4 complex subunit p50
Extra Details:: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]