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GTX68421-PRO

Human DCPS protein, His tag

Cannot supply to this region.

SKU:
GTX68421-PRO
Additional Names:
decapping enzyme, scavenger , ARS , DCS1 , HINT-5 , HINT5 , HSL1 , HSPC015
Concentration:
0.5 mg/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
20mM Tris-HCl, 20% Glycerol, 1mM DTT, no preservatives.
Immunogen:
decapping enzyme, scavenger
Species:
Human
Uniprot:
Q96C86
Synonyms:
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase;ARS;DCS-1;DCS1;decapping scavenger enzyme;epididymis secretory sperm binding protein;heat shock-like protein 1;HINT-5;hint-related 7meGMP-directed hydrolase;HINT5;histidine triad nucleotide-binding protein 5;histidine triad protein member 5;homolog of C. elegans 7meGMP-directed hydrolase dcs-1;HSL1;HSPC015;m7GpppX diphosphatase;mRNA decapping enzyme;scavenger mRNA-decapping enzyme DcpS
Extra Details:
This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. [provided by RefSeq, Apr 2017]
Shipping Conditions:
Dry Ice