GTX68375-PRO
Human BRDG1 protein, His tag
Cannot supply to this region.
- SKU:
- GTX68375-PRO
- Additional Names:
- signal transducing adaptor family member 1 , BRDG1 , STAP-1
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 30% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- signal transducing adaptor family member 1
- Species:
- Human
- Uniprot:
- Q9ULZ2
- Synonyms:
- BCR downstream-signaling protein 1;BRDG1;docking protein BRDG1;signal-transducing adaptor protein 1;STAP-1;stem cell adaptor protein 1
- Extra Details:
- The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Shipping Conditions:
- Dry Ice