GTX68260-PRO
Mouse eIF4E protein, His tag
Cannot supply to this region.
- SKU:
- GTX68260-PRO
- Additional Names:
- eukaryotic translation initiation factor 4E , EG668879 , Eif4e-ps , If4e , eIF-4E
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 1mM DTT, 0.1mM PMSF, no preservatives.
- Immunogen:
- eukaryotic translation initiation factor 4E
- Species:
- Mouse
- Uniprot:
- P63073
- Synonyms:
- EG668879;eIF-4;eIF-4E;eIF-4F 25 kDa subunit;Eif4e-ps;eukaryotic translation initiation factor 4E;If4;If4e;mRNA cap-binding protein
- Extra Details:
- This gene encodes a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. It has also been associated with autism spectrum disorders. Consistently, knockout of this gene results in increased translation of neuroligins, postsynaptic proteins linked to autism spectrum disorders. Pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Shipping Conditions:
- Dry Ice