Human BPNT1 protein, His tag

Cannot supply to this region.

SKU:: GTX68146-PRO
Additional Names:: 3'(2'), 5'-bisphosphate nucleotidase 1 , HEL20 , PIP
Concentration:: 0.5 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 5mM DTT, no preservatives.
Immunogen:: 3'(2'), 5'-bisphosphate nucleotidase 1
Species:: Human
Uniprot:: O95861
Synonyms:: 3'(2'),5'-bisphosphate nucleotidase 1;bisphosphate 3'-nucleotidase 1;BPntase;epididymis luminal protein 20;HEL20;PAP-inositol 1,4-phosphatase;PAP-inositol-1,4-phosphatase;PIP;testicular tissue protein Li 29
Extra Details:: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]